Adenosine Triphosphate : Guanosine Monophosphate Phosphotransferase
نویسندگان
چکیده
Several laboratories have reported studies on individual enzymes that belong to the general class of adenosine triphosphate : nucleoside monophosphate phosphotransferases (EC 2.7.4.4), commonly termed nucleoside monophosphate kinases (l-7). Studies with partially purified enzyme preparations have indicated that a variety of nucleoside monophosphates can serve as alternative substrates for nucleoside monophosphate kinases from various tissues (1, 6, 7). As part of a study of the effects of carcinostatic purine analogues on nucleotide metabolism, an investigation of the biosynthesis of guanosine diphosphate from guanosine phosphate was undertaken in this laboratory. An enzyme, which may be termed adenosine triphosphate : guanosine monophosphate phosphotransferase, was purified from hog brain and catalyzes the following reaction:
منابع مشابه
Adenosine triphosphate: adenosine monophosphate phosphotransferase isozymes in rat liver and hepatomas.
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